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Using two separate drugs to lose weight naturally can be very effective you will find combinations before the FDA now awaiting approval. When dealing with weight-loss and the people that go through it one should err along the side of caution and allow FDA do its job and demand some investigation be done so that the public recognizes the side effects and risks of the medications before we take them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on the medications. Researchers discovered that participants using this drug to get a year, lost weight within four weeks and have kept the weight off through the entire 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which are made up of many active ingredient, which can make them more effective and safer. Combo-pilling is the newest fad or in addition to this the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that as of right now there aren't any long term prescription slimming capsules that have been licensed by the FDA other than orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures really are a side effect with Contrave and must not be taken in those with seizure disorders. The drug also can raise blood pressure level and heart rate, and shouldn't be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not be used in patients with uncontrolled high blood pressure, and also by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients with a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation. Acamprosate also actively works to eliminate the want to drink through the elimination of the the cravings for drinking alcohol. The major difference between Naltrexone and Acamprosate is always that Acamprosate is not yet obtainable in the United States. While it continues to be widely studied in Europe the complete chemical believe that it works remains unknown. It is believed that it interferes with receptors in the brain which process glutamate, which in place alters the way ones body reacts to alcohol intake. Several of the European studies show a lot of promise with Acamprosate because some of the patients had an almost double effectiveness for staying sober.